Surrogate markers for cerebral blood flow correlate with [¹⁸F]-fallypride binding potential at dopamine D(2/3) receptors in human striatum.

@article{Cumming2013SurrogateMF,
  title={Surrogate markers for cerebral blood flow correlate with [¹⁸F]-fallypride binding potential at dopamine D(2/3) receptors in human striatum.},
  author={Paul Cumming and Guoming Xiong and Christian la Foug{\'e}re and Axel Rominger and Peter Bartenstein and Hans-Georg Buchholz and Markus Piel and Frank Roesch and Gerhard Gr{\"u}nder and Ingo Vernaleken},
  journal={Synapse},
  year={2013},
  volume={67 4},
  pages={199-203}
}
Positron emission tomography (PET) with the high affinity dopamine D(2/3) receptor ligand [¹⁸F]-fallypride affords estimates of the binding potential (BP(ND) ) in extra-striatal regions of low receptor abundance, but the sufficient recording time for accurate measurements in striatum has been called into question. We have earlier argued that transient equilibrium measurements are obtained in striatum with [¹⁸F]-fallypride PET recordings of 3 h duration, which may be the practical limit for… CONTINUE READING
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