Surrogate estimates of insulin sensitivity in obese youth along the spectrum of glucose tolerance from normal to prediabetes to diabetes.

@article{George2011SurrogateEO,
  title={Surrogate estimates of insulin sensitivity in obese youth along the spectrum of glucose tolerance from normal to prediabetes to diabetes.},
  author={Lindsey A George and Fida Bacha and Sojung Lee and Hala M Tfayli and Elisa Andreatta and Silva S Arslanian},
  journal={The Journal of clinical endocrinology and metabolism},
  year={2011},
  volume={96 7},
  pages={2136-45}
}
CONTEXT In epidemiological studies of childhood obesity, simple and reliable surrogate estimates of insulin sensitivity are needed because the gold standard, the hyperinsulinemic-euglycemic clamp, is not feasible on a large scale. OBJECTIVE To examine the correlation of fasting and oral glucose tolerance test (OGTT)-derived surrogate indices of insulin sensitivity with the hyperinsulinemic-euglycemic clamp in obese adolescents with normal glucose tolerance, prediabetes, and diabetes… CONTINUE READING
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