Surrogate end points in heart failure.

  title={Surrogate end points in heart failure.},
  author={Craig R. Lee and Kirkwood F. Adams and James H. Patterson},
  journal={The Annals of pharmacotherapy},
  volume={36 3},
OBJECTIVE To describe the potential utility of a true surrogate marker of heart failure outcomes, historically investigate the validity of surrogates most commonly evaluated in heart failure, and identify specific end points offering the most potential for future use. DATA SOURCES A MEDLINE search (1966-June 2001) was completed to identify relevant literature. Additional references were also retrieved from selected articles. Search terms included b-type natriuretic peptide, cardiac remodeling… CONTINUE READING


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