Surprises from Drosophila: genetic mechanisms of synaptic development and plasticity.

@article{Featherstone2000SurprisesFD,
  title={Surprises from Drosophila: genetic mechanisms of synaptic development and plasticity.},
  author={David E Featherstone and Kendal Broadie},
  journal={Brain research bulletin},
  year={2000},
  volume={53 5},
  pages={501-11}
}
Drosophila are excellent models for the study of synaptic development and plasticity, thanks to the availability and applicability of a wide variety of powerful molecular, genetic, and cell-biology techniques. Three decades of study have led to an intimate understanding of the sequence of events leading to a functional and plastic synapse, yet many of the molecular mechanisms underlying these events are still poorly understood. Here, we provide a review of synaptogenesis at the Drosophila… CONTINUE READING