Surgical treatment of gastric cancer: 15-year follow-up results of the randomised nationwide Dutch D1D2 trial.

@article{Songun2010SurgicalTO,
  title={Surgical treatment of gastric cancer: 15-year follow-up results of the randomised nationwide Dutch D1D2 trial.},
  author={Ilfet Songun and Hein Putter and E. Meershoek klein Kranenbarg and Mitsuru Sasako and Cornelis J H van de Velde},
  journal={The Lancet. Oncology},
  year={2010},
  volume={11 5},
  pages={
          439-49
        }
}
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39 References

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The findings indicate that the classical Japanese D2 resection offers no survival advantage over D1 surgery, however, the possibility that D 2 resection without pancreatico-splenectomy may be better than standard D1 resection cannot be dismissed by the results of this trial.

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A survival benefit for pancreas-preserving D2 dissection in Italian patients with gastric cancer if performed in experienced centres is suggested, and a phase III study comparing D1 vs D1 dissection for curable Gastric cancer is urgently needed.

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It is concluded that in this trial low- MI surgery is associated with enhanced survival, whereas outside of certain subgroups routine D2 lymphadenectomy is not, suggesting that surgeons might have more of an impact on patient survival by achieving a low-MI operation than a particular D level.

Surgical treatment variation in a prospective, randomized trial of chemoradiotherapy in gastric cancer: The effect of undertreatment

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