Surgical site infections in orthopedic surgery: the effect of mupirocin nasal ointment in a double-blind, randomized, placebo-controlled study.

@article{Kalmeijer2002SurgicalSI,
  title={Surgical site infections in orthopedic surgery: the effect of mupirocin nasal ointment in a double-blind, randomized, placebo-controlled study.},
  author={Mathijs D. Kalmeijer and H Coertjens and P M van Nieuwland-Bollen and Diana Bogaers-Hofman and G A J de Baere and Arie Stuurman and Alex van Belkum and Jan A. J. W. Kluytmans},
  journal={Clinical infectious diseases : an official publication of the Infectious Diseases Society of America},
  year={2002},
  volume={35 4},
  pages={353-8}
}
The objective of this study was to determine whether use of mupirocin nasal ointment for perioperative eradication of Staphylococcus aureus nasal carriage is effective in preventing the development of surgical site infections (SSIs). A randomized, double-blind, placebo-controlled design was used. Either mupirocin or placebo nasal ointment was applied twice daily to 614 assessable patients from the day of admission to the hospital until the day of surgery. A total of 315 and 299 patients were… CONTINUE READING

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