Surgical resection plus stereotactic 125I brachytherapy in adult patients with eloquently located supratentorial WHO grade II glioma – Feasibility and outcome of a combined local treatment concept

@article{Schnell2008SurgicalRP,
  title={Surgical resection plus stereotactic 125I brachytherapy in adult patients with eloquently located supratentorial WHO grade II glioma – Feasibility and outcome of a combined local treatment concept},
  author={Oliver Schnell and Karsten Sch{\"o}ller and Maximilian Ruge and Axel Siefert and J C Tonn and Friedrich Wilhelm Kreth},
  journal={Journal of Neurology},
  year={2008},
  volume={255},
  pages={1495-1502}
}
The current pilot study analyzed feasibility, risk and effectiveness of 1) microsurgery plus stereotactic iodine-125 (125I) brachytherapy (SBT) for large (diameter > 4 cm), circumscribed, and complex located WHO grade II glioma and 2) SBT alone for small (diameter < 4 cm), and complex located recurrences. Lowactivity temporary 125I seeds were used. The applied reference dose was 54 Gy and the dose rate was low (median, 10 cGy/h). Time to progression and time to additional external beam… CONTINUE READING

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