Surgical manipulation of the large intestine increases bacterial translocation in patients undergoing elective colorectal surgery.

@article{Reddy2006SurgicalMO,
  title={Surgical manipulation of the large intestine increases bacterial translocation in patients undergoing elective colorectal surgery.},
  author={B. Venkata Suresh Reddy and Marcel Gatt and Ravi Sowdi and John Macfie},
  journal={Colorectal disease : the official journal of the Association of Coloproctology of Great Britain and Ireland},
  year={2006},
  volume={8 7},
  pages={596-600}
}
OBJECTIVE Several animal studies have suggested that surgical manipulation of the intestine alters the barrier function and promotes bacterial translocation (BT). Whether this occurs in humans has never been investigated. The aim of this study was to determine the effect of surgical manipulation of the intestine on the prevalence of BT in patients undergoing elective colorectal surgery. METHOD This was a prospective observational study of 50 consecutive elective surgical patients in whom a… CONTINUE READING

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