Surgical manipulation of VX2 carcinoma in the rabbit liver evokes enhancement of metastasis.

@article{Nishizaki1990SurgicalMO,
  title={Surgical manipulation of VX2 carcinoma in the rabbit liver evokes enhancement of metastasis.},
  author={Takashi Nishizaki and Takashi Matsumata and Takashi Kanematsu and Chikao Yasunaga and Keizo Sugimachi},
  journal={The Journal of surgical research},
  year={1990},
  volume={49 1},
  pages={92-7}
}
To search for possible untoward effects of surgical manipulation of a malignant tumor, a series of experiments was carried out using VX2 carcinoma of rabbits. Fourteen days after inoculation of VX2 carcinoma into the liver, the rabbits were separated into two groups: Group I, manual manipulation during relaparotomy; and Group II, relaparotomy alone without manual manipulation of the tumor. After these procedures, the tumor was surgically removed and histologic examinations were made. The… CONTINUE READING

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