Surgical management of metastatic bone disease.

@article{Bickels2009SurgicalMO,
  title={Surgical management of metastatic bone disease.},
  author={Jacob Bickels and Shlomo Dadia and Zvi Lidar},
  journal={The Journal of bone and joint surgery. American volume},
  year={2009},
  volume={91 6},
  pages={
          1503-16
        }
}
Metastatic bone disease is a major contributor to the deterioration of the quality of life of patients with cancer; it causes pain, impending and actual pathological fractures, and loss of function and may also be associated with considerable metabolic alterations. Operative treatment may be required for an impending or existing fracture and intractable pain. The goals of surgery are to provide local tumor control and allow immediate weight-bearing and function. Radiation therapy is often… 
Metastatic Bone Disease
TLDR
Through an understanding of these factors, the orthopaedic surgeon can use techniques that maximize the likelihood of creating a lasting, stable construct, resulting in elimination pain and rapid return of patients to function.
The role of postoperative radiation and coordination of care in patients with metastatic bone disease of the appendicular skeleton
TLDR
The role of radiation therapy after orthopaedic stabilization of impending or realized pathologic extremity fractures and the effect on clinical outcomes in this population is reviewed.
Pathological and Impending Fracture
TLDR
This chapter will review the role of surgery in the management of skeletal metastases and discuss factors that should be considered prior to surgery, along with novel approaches to more accurately guide fracture risk prediction radiologically.
Management of periacetabular metastatic disease
TLDR
The principles and designs of surgical constructs have not changed substantially over the past decade and the current concepts and trends in the evaluation and management of periacetabular metastatic disease are reviewed.
Identifying impending pathologic fractures and treatment considerations in patients with metastatic bone disease
TLDR
This review focuses on the early identification of high-risk tumors before fracture occurs and discusses treatment options.
Surgical outcomes of metastatic bone tumors in the extremities (Surgical outcomes of bone metastases)
Metastases to the Pelvis: Algorithm of Treatment
TLDR
This algorithm aims to simplify the choices of the team from diagnosis to treatment and to avoid under- or overtreatment of pelvic bone metastases.
Management of Bone Metastases in Patients with Castration-Resistant Prostate Cancer
TLDR
Evaluation of currently available treatment options in the prevention and management of SREs and bone metastases in men with castration-resistant prostate cancer and the importance of interdisciplinary management strategies are outlined.
Team Approach: The Treatment of Metastatic Tumors of the Femoral Diaphysis
TLDR
Nonoperative interventions include chemotherapy, bone-modulating agents such as bisphosphonates and denosumab, radiation therapy, and ablation with cementoplasty, and Postoperative external-beam radiation is indicated for local disease control.
...
1
2
3
4
5
...

References

SHOWING 1-10 OF 162 REFERENCES
Management of metastatic disease of other bones.
Incidence, location, and diagnostic evaluation of metastatic bone disease.
Management of metastatic lesions of the humerus.
Clinical Features of Metastatic Bone Disease and Risk of Skeletal Morbidity
TLDR
Improved understanding of prognostic and predictive factors may enable delivery of a more personalized treatment for the individual patient and a more cost-effective use of health care resources.
Operative management of metastases to the pelvis and acetabulum.
The management of pathological fracture of the major long bones from metastatic cancer.
TLDR
It is concluded that internal fixation and radiotherapy is the best method at present available for dealing with a pathological fracture of a major long bone through a metastatic cancer deposit.
Radiation for bone metastases
TLDR
An Interdisciplinary Bone Metastases Clinic was developed that allows coordinated evaluation, treatment, and symptom management of these complex clinical presentations.
SKELETAL METASTASIS IN CANCER
TLDR
Metastasis to bone may occur many years following the primary operation, and in the present series of cases of breast cancer skeletal metastasis was observed as late as eighteen and twenty-five hundredths years postoperatively.
Proximal femoral replacement for metastatic bone disease.
TLDR
Proximal femoral replacement provides excellent pain relief and good restoration of function when more simple reconstructive options are not feasible.
...
1
2
3
4
5
...