Surgery-triggered and non surgery-triggered Bisphosphonate-related Osteonecrosis of the Jaws (BRONJ): A retrospective analysis of 567 cases in an Italian multicenter study.

@article{Vescovi2011SurgerytriggeredAN,
  title={Surgery-triggered and non surgery-triggered Bisphosphonate-related Osteonecrosis of the Jaws (BRONJ): A retrospective analysis of 567 cases in an Italian multicenter study.},
  author={Paolo Vescovi and Giuseppina Campisi and Vittorio Fusco and Giovanni Mergoni and Maddalena Manfredi and Elisabetta Merigo and Luigi Solazzo and Mario Gabriele and Giovanni Maria Gaeta and Gianfranco Favia and Franco Peluso and Giuseppe Colella},
  journal={Oral oncology},
  year={2011},
  volume={47 3},
  pages={191-4}
}
Invasive local procedures are often reported in clinical history of patients suffering from Bisphosphonates-Related Osteonecrosis of the Jaws (BRONJ) but over 40% of spontaneous forms have been also described in literature. We compared age, gender, underlying bone disorders, bisphosphonate therapy, clinical features and surgical outcome of 205 cases (36.2%) of BRONJ non surgery-triggered (group 1) with 362 (63.8%) cases of surgery-triggered forms (group 2). Differences between group 1 and 2… CONTINUE READING