Surgery guided by 5-aminolevulinic fluorescence in glioblastoma: volumetric analysis of extent of resection in single-center experience

@article{Valle2010SurgeryGB,
  title={Surgery guided by 5-aminolevulinic fluorescence in glioblastoma: volumetric analysis of extent of resection in single-center experience},
  author={Ricardo D{\'i}ez Valle and Sonia Tejada Solis and Miguel Angel Idoate Gastearena and Reyes Garc{\'i}a de Eulate and Pablo Dom{\'i}nguez Ech{\'a}varri and Javier Aristu Mendiroz},
  journal={Journal of Neuro-Oncology},
  year={2010},
  volume={102},
  pages={105-113}
}
We analyzed the efficacy and applicability of surgery guided by 5-aminolevulinic acid (ALA) fluorescence in consecutive patients with glioblastoma multiforme (GBM). Thirty-six patients with GBM were operated on using ALA fluorescence. Resections were performed using the fluorescent light to assess the right plane of dissection. In each case, biopsies with different fluorescent quality were taken from the tumor center, from the edges, and from the surrounding tissue. These samples were analyzed… CONTINUE READING