Surfactants selectively ablate enteric neurons of the rat jejunum.

@article{Fox1983SurfactantsSA,
  title={Surfactants selectively ablate enteric neurons of the rat jejunum.},
  author={Darrell Fox and Miles L. Epstein and Paul Bass},
  journal={The Journal of pharmacology and experimental therapeutics},
  year={1983},
  volume={227 2},
  pages={538-44}
}
Surfactants, a group of nonspecific membrane perturbating substances, can cause nerve damage. Various concentrations of the cationic surfactants benzalkonium chloride (BAC) and benzethonium chloride, the anionic surfactants sodium ricinoleate, dioctyl sodium sulfosuccinate and sodium lauryl sulfate and the nonionic surfactant Triton X-100 were applied to the serosal surface of the rat jejunum every 5 min for 0.5 hr and then rinsed off with saline. Thirty days after surfactant application, the… CONTINUE READING
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