Surfactants, Salt, and pH Alter Nanoparticle-Model Cell Membrane Interactions
@inproceedings{Brennan2014SurfactantsSA,
title={Surfactants, Salt, and pH Alter Nanoparticle-Model Cell Membrane Interactions},
author={Katie Brennan and Luke Cuculis and Shelli L. Frey},
year={2014}
}Due to their small size, nanoparticles have the ability to penetrate pulmonary and vascular tissue, and as a result, are classified as potential human carcinogens. On the other hand, nanoparticle insertion into targeted cells can play a key role in drug delivery and gene therapy applications, prompting a need to more thoroughly characterize nanoparticle/membrane interactions. Polystyrene nanoparticles with modifications in surface functionalization and detergent conditions remain monodisperse… CONTINUE READING