Surfactant with SP-B and SP-C analogues improves lung function in surfactant-deficient rats.

@article{Walther2002SurfactantWS,
  title={Surfactant with SP-B and SP-C analogues improves lung function in surfactant-deficient rats.},
  author={Frans J. Walther and Jos{\'e} M. Hern{\'a}ndez-Juviel and Pamela E Mercado and Larry M. Gordon and Alan J. Waring},
  journal={Biology of the neonate},
  year={2002},
  volume={82 3},
  pages={181-7}
}
The use of mammalian lung surfactant extracts has sharply reduced mortality and morbidity from respiratory distress syndrome in premature infants. Synthesis of surfactant protein B and C (SP-B and SP-C) analogues may lead the way to a synthetic surfactant preparation. Dimeric SP-B(1-25) (dSP-B(1-25)) is based on the N-terminal domain of human SP-B and SP… CONTINUE READING