Surfactant protein D in atopic dermatitis and psoriasis.

  title={Surfactant protein D in atopic dermatitis and psoriasis.},
  author={Thomas Hohwy and Kristian Otkjaer and Jens Christian Bredahl Madsen and Gritt S\oerensen and Ole A. Nielsen and Christian L. Vestergaard and Torben Steiniche and Uffe Holmskov and Hans Bredsted Lomholt},
  journal={Experimental dermatology},
  volume={15 3},
The collectin surfactant protein-D (SP-D) shows antimicrobial and immuno-regulatory properties and has recently been detected in the basal layers of normal human skin. This molecule potentially plays an important role in inflammatory skin diseases and therefore SP-D content and location was examined using immunohistochemistry on skin biopsies from patients with the two major dermatologic diseases, psoriasis and atopic dermatitis. SP-D was located in the stratum basale of all biopsies with… CONTINUE READING


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