Surfactant protein-D and pulmonary host defense

  title={Surfactant protein-D and pulmonary host defense},
  author={Erika C. Crouch},
  journal={Respiratory Research},
  pages={93 - 108}
Surfactant protein-D (SP-D) participates in the innate response to inhaled microorganisms and organic antigens, and contributes to immune and inflammatory regulation within the lung. SP-D is synthesized and secreted by alveolar and bronchiolar epithelial cells, but is also expressed by epithelial cells lining various exocrine ducts and the mucosa of the gastrointestinal and genitourinary tracts. SP-D, a collagenous calcium-dependent lectin (or collectin), binds to surface glycoconjugates… CONTINUE READING
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