Surfactant-induced amorphous aggregation of tobacco mosaic virus coat protein: a physical methods approach.

@article{Panyukov2008SurfactantinducedAA,
  title={Surfactant-induced amorphous aggregation of tobacco mosaic virus coat protein: a physical methods approach.},
  author={Yuliy V Panyukov and Maria A Nemykh and Eugeny N. Dobrov and V. A. Drachev},
  journal={Macromolecular bioscience},
  year={2008},
  volume={8 2},
  pages={199-209}
}
The interactions of non-ionic surfactant Triton X-100 and the coat protein of tobacco mosaic virus, which is an established model for both ordered and non-ordered protein aggregation, were studied using turbidimetry, differential scanning calorimetry, isothermal titration calorimetry, and dynamic light scattering. It was found that at the critical aggregation concentration (equal to critical micelle concentration) of 138 x 10(-6) M, Triton X-100 induces partial denaturation of tobacco mosaic… CONTINUE READING