Surfactant-associated proteins (SP-A, SP-B) are increased proportionally to alveolar phospholipids in sheep silicosis

@article{Lesur1993SurfactantassociatedP,
  title={Surfactant-associated proteins (SP-A, SP-B) are increased proportionally to alveolar phospholipids in sheep silicosis},
  author={Olivier Lesur and Rudy A. W. Veldhuizen and Jeff A. Whitsett and William M. Hull and Fred Possmayer and Andr{\'e} Cantin and Raymond O. Begin},
  journal={Lung},
  year={1993},
  volume={171},
  pages={63-74}
}
In silicosis, a profile of surfactant overproduction associated with type II epithelial cell hypertrophy and hyperplasia has been documented. In addition, enhanced accumulation of surfactant-associated protein A (SP-A) has been seen in the rat model of acute silicosis by 2 independent groups, but the exact role of these surfactant changes in silicosis are incompletely understood. In this study we measured in lung lavage surfactant total phospholipids and surfactant-associated proteins A and B… CONTINUE READING
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Changes in suffactant - associated protein A resulting from asbestos exposure

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Changes in suffactant-associated protein

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