Surfactant Apoprotein A Modifies the Inhibitory Effect of Plasma Proteins on Surfactant Activity In Vivo

Abstract

ABSTRACT: Surfactant apoprotein A (SP-A) reduces the inhibitory effects of plasma proteins on the surface tension lowering properties of pulmonary surfactant in vitro. To test the effects of SP-A in vivo we administered a complete natural dog lung surfactant (DLS) containing apoproteins SP-A, SP-B, and SP-C, a butanol extract of DLS (DLSE) containing only… (More)
DOI: 10.1203/00006450-199501000-00005

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