Surface proteins of Plasmodium falciparum merozoites binding to the erythrocyte receptor, glycophorin

@article{Perkins1984SurfacePO,
  title={Surface proteins of Plasmodium falciparum merozoites binding to the erythrocyte receptor, glycophorin},
  author={Margaret E Perkins},
  journal={The Journal of Experimental Medicine},
  year={1984},
  volume={160},
  pages={788 - 798}
}
Invasion of erythrocytes by the malarial parasite is a receptor-mediated process. P. falciparum merozoites recognize and bind to erythrocyte surface sialoglycoproteins, glycophorins A and B, and the glycophorins bind to saturable sites on the merozoite surface. The purpose of the present work was to identify a receptor or ligand molecule on the merozoite surface that mediates binding to the erythrocyte. A fraction containing the sialoglycoproteins was coupled to an acrylamide matrix and… CONTINUE READING