Surface properties of cells isolated from non-metastasizing and metastasizing hamster lymphosarcomas.

@article{Guy1980SurfacePO,
  title={Surface properties of cells isolated from non-metastasizing and metastasizing hamster lymphosarcomas.},
  author={Duncan Guy and Albert L. Latner and G. V. Sherbet and Graham A. Turner},
  journal={British Journal of Cancer},
  year={1980},
  volume={42},
  pages={915 - 921}
}
Present evidence suggests that the cell surface has an important role in metastasis. To examine this idea further, the surface properties of single cells isolated from the primary growths of a liver-metastasizing (ML) and a non-metastasizing (NML) lymphosarcoma were compared for adhesion to cell monolayers, cytopherometry, isoelectric focusing, adhesion to immobilized lectins and surface labelling with lactoperoxidase-catalysed radioiodination. It was found that the ML cells had increased… CONTINUE READING