Surface plasmon resonance measurements of plasma antibody avidity during primary and secondary responses to anthrax protective antigen.


Establishment of humoral immunity against pathogens is dependent on events that occur in the germinal center and the subsequent induction of high-affinity neutralizing antibodies. Quantitative assays that allow monitoring of affinity maturation and duration of antibody responses can provide useful information regarding the efficacy of vaccines and adjuvants… (More)
DOI: 10.1016/j.jim.2013.11.026


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