Surface plasmon resonance mass spectrometry in proteomics

  title={Surface plasmon resonance mass spectrometry in proteomics},
  author={N. F. Visser and A. Heck},
  journal={Expert Review of Proteomics},
  pages={425 - 433}
  • N. F. Visser, A. Heck
  • Published 2008
  • Chemistry, Medicine
  • Expert Review of Proteomics
  • Due to the enormous complexity of the proteome, focus in proteomics shifts more and more from the study of the complete proteome to the targeted analysis of part of the proteome. The isolation of this specific part of the proteome generally includes an affinity-based enrichment. Surface plasmon resonance (SPR), a label-free technique able to follow enrichment in real-time and in a semiquantitative manner, is an emerging tool for targeted affinity enrichment. Furthermore, in combination with… CONTINUE READING
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