Surface plasmon resonance imaging for affinity-based biosensors.

  title={Surface plasmon resonance imaging for affinity-based biosensors.},
  author={Simona Scarano and Marco Mascini and Anthony P Turner and Maria Minunni},
  journal={Biosensors & bioelectronics},
  volume={25 5},
SPR imaging (SPRi) is at the forefront of optical label-free and real-time detection. It offers the possibility of monitoring hundreds of biological interactions simultaneously and from the binding profiles, allows the estimation of the kinetic parameters of the interactions between the immobilised probes and the ligands in solution. We review the current state of development of SPRi technology and its application including commercially available SPRi instruments. Attention is also given to… CONTINUE READING