Surface plasmon resonance for rapid screening of uranyl affine proteins.

Abstract

A sensitive immunoassay based on SPR analysis was developed to measure uranyl cation (UO(2)(2+)) affinity for any protein in a free state under physiological conditions. The technique involves immobilization of a specific monoclonal antibody (mAb) raised against UO(2)(2+) and 1,10-phenanthroline-2,9-dicarboxylic acid (DCP) used as a probe of UO(2)(2… (More)
DOI: 10.1021/ac102578y

6 Figures and Tables

Topics

  • Presentations referencing similar topics