Surface phenotype of clonogenic cells in acute myeloid leukemia defined by monoclonal antibodies.

@article{Lange1984SurfacePO,
  title={Surface phenotype of clonogenic cells in acute myeloid leukemia defined by monoclonal antibodies.},
  author={Bj{\"o}rn Lange and Dario Ferrero and Silvana Pessano and Angela Palumbo and Jan Faust and Pacifico Meo and Giuseppe Rovera},
  journal={Blood},
  year={1984},
  volume={64 3},
  pages={693-700}
}
Colony-forming cells in ten cases of acute myeloid leukemia (AML) were studied with six cytotoxic monoclonal antibodies that react with antigens expressed at discrete stages of differentiation of normal and leukemic hematopoietic cells. The reactivity of the whole leukemic population was measured by indirect immunofluorescence, and the reactivity of the colony-forming cells was established by complement-mediated cytotoxicity and by fluorescence activated cell sorting. Comparison of the… CONTINUE READING
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