Surface passivation of zero-mode waveguide nanostructures: benchmarking protocols and fluorescent labels

  title={Surface passivation of zero-mode waveguide nanostructures: benchmarking protocols and fluorescent labels},
  author={Satyajit Patra and Mikhail Baibakov and Jean-Beno{\^i}t Claude and J{\'e}r{\^o}me Wenger},
  journal={Scientific Reports},
Zero mode waveguide (ZMW) nanoapertures efficiently confine the light down to the nanometer scale and overcome the diffraction limit in single molecule fluorescence analysis. However, unwanted adhesion of the fluorescent molecules on the ZMW surface can severely hamper the experiments. Therefore a proper surface passivation is required for ZMWs, but information is currently lacking on both the nature of the adhesion phenomenon and the optimization of the different passivation protocols. Here we… 

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