Surface movements during the spreading of blood platelets.

  title={Surface movements during the spreading of blood platelets.},
  author={O. Behnke and Dennis Bray},
  journal={European journal of cell biology},
  volume={46 2},
When human blood platelets spread on a substratum they increase their surface area as much as 4-fold. We investigated the mechanism of spreading by light microscopy and by scanning and transmission electron microscopy. Contact of a platelet with a glass surface induces formation of thin extensions which spread out over the substratum. These extensions resemble the actin-containing microspikes and lammelipodia of tissue cells in culture and appear to be drawn from the peripheral cortical layer… CONTINUE READING