Surface morphology and agglutinability with concanavalin A in normal and transformed murine fibroblasts

@article{Collard1976SurfaceMA,
  title={Surface morphology and agglutinability with concanavalin A in normal and transformed murine fibroblasts},
  author={John G. Collard and J. H. M. Temmink},
  journal={The Journal of Cell Biology},
  year={1976},
  volume={68},
  pages={101 - 112}
}
The surface morphology of attached and suspended normal and transformed fibroblasts has been studied with the scanning electron microscope. Normal murine fibroblasts (3T3) grow in vitro with widely extended leading lamellae. During most parts of the cell cycle the surfaces of these cells are practically free of microvilli. When the cells round up for mitosis, their cell surfaces become adorned with many microvilli. In contrast, simian virus 40-transformed fibroblasts (SV3T3) grow more compact… CONTINUE READING
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