Surface modified nevirapine nanosuspensions for viral reservoir targeting: In vitro and in vivo evaluation.

@article{Shegokar2011SurfaceMN,
  title={Surface modified nevirapine nanosuspensions for viral reservoir targeting: In vitro and in vivo evaluation.},
  author={R. Shegokar and K. Singh},
  journal={International journal of pharmaceutics},
  year={2011},
  volume={421 2},
  pages={
          341-52
        }
}
Most of the time HIV virus escape immunological burden exerted by antiretroviral drugs and develops resistance against therapy. For complete eradication of virus from body one has to use long term chemotherapies, which results in drug toxicity, drug resistance and eventually poor patient compliance. Nevirapine (NNRTI, non nucleoside reverse transcriptase inhibitor) nanosuspensions were developed and surface modified with serum albumin, polysaccharide and polyethylene glycol to enhance its… Expand
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