Surface modification of iron oxide nanoparticles by biocompatible polymers for tissue imaging and targeting.

  title={Surface modification of iron oxide nanoparticles by biocompatible polymers for tissue imaging and targeting.},
  author={Muthunarayanan Muthiah and In-Kyu Park and Chong-su Cho},
  journal={Biotechnology advances},
  volume={31 8},
Superparamagnetic iron oxide nanoparticles (SPIONs) are excellent MR contrast agents when coated with biocompatible polymers such as hydrophilic synthetic polymers, proteins, polysaccharides, and lipids, which improve their stability and biocompatibility and reduce their aggregation. Various biocompatible materials, coated or conjugated with targeting moieties such as galactose, mannose, folic acid, antibodies and RGD, have been applied to SPION surfaces to provide tissue specificity to… CONTINUE READING


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Publications referenced by this paper.
Showing 1-10 of 66 references

Agent for Magnetic Resonance Imaging

WJ Hsieh, CJ Liang, +3 authors JH Chen
J Korean Phys Soc • 2012
View 1 Excerpt

Carboxylic mannan-coated iron oxide nanoparticles targeted to immune cells for lymph node-specific MRI in vivo

H Vu-Quang, M Muthiah, +3 authors WJ Kim
Carbohyd Polym. 2012a;88:780-8 • 2012
View 1 Excerpt

Interactions and in Vivo Biodistribution: Impact of Surface PEG and Ligand Properties

J Ren, Y Miao, J Wang, E. Wang
Biosens Bioelectron • 2012

PEGylation conditions for BSA nanoparticles using response surface methodology. AAPS PharmSciTech

N Kuehnert, NA Kraemer, +3 authors M Baumann
Surg Endosc • 2012
View 1 Excerpt

PEGylation of supercooled smectic cholesteryl myristate nanoparticles.

European journal of pharmaceutics and biopharmaceutics : official journal of Arbeitsgemeinschaft fur Pharmazeutische Verfahrenstechnik e.V • 2012
View 1 Excerpt

Surface-imprinted chitosan-coated magnetic nanoparticles modified multi-walled carbon nanotubes biosensor for detection of bovine serum albumin. Sensor Actuat B-Chem

HJ Chen, ZH Zhang, LJ Luo, SZ. Yao
View 1 Excerpt

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