Surface modification for improved blood compatibility.

  title={Surface modification for improved blood compatibility.},
  author={Harvey Jacobs and David L Grainger and Teruo Okano and Sung Wan Kim},
  journal={Artificial organs},
  volume={12 6},
Several surface modification techniques are currently being used to improve the biocompatibility of blood-contacting devices. These include the immobilization of bioactive materials to prevent thrombus generation and platelet activation, the incorporation of hydrophilic grafts onto practical hydrophobic surfaces (polyurethanes) to reduce protein adsorption, and the concept of microdomain-phase separated surfaces to regulate cellular and protein adhesion.