Surface manipulation of biomolecules for cell microarray applications.

  title={Surface manipulation of biomolecules for cell microarray applications.},
  author={Andrew Leslie Hook and Helmut Thissen and Nicolas H. Voelcker},
  journal={Trends in biotechnology},
  volume={24 10},
Many biological events, such as cellular communication, antigen recognition, tissue repair and DNA linear transfer, are intimately associated with biomolecule interactions at the solid-liquid interface. To facilitate the study and use of these biological events for biodevice and biomaterial applications, a sound understanding of how biomolecules behave at interfaces and a concomitant ability to manipulate biomolecules spatially and temporally at surfaces is required. This is particularly true… CONTINUE READING