Understanding the mechanism of nanosilver-dependent antibacterial activity against microorganisms helps optimize the design and usage of the related nanomaterials. In this study, we prepared four kinds of 10 nm-sized silver nanoparticles (AgNPs) with dictated surface chemistry by capping different ligands, including citrate, mercaptopropionic acid… (More)
Figure 3 The viabilities of E. coli after 6-h exposures of different agNPs. Notes: (A) agNP treatment alone, (B) The coexposure of agNPs and 1 mM gsh, (C) The coexposure of agNPs and 0.1 mM Na2s2O3, and (D) The exposure of ag + in the absence or presence of 1 mM gsh or 0.1 mM Na2s2O3. aDenotes significant difference between each AgNP exposure group and the negative control (P,0.05). bDenotes significant difference between each AgNP (1 μg/ml) plus gsh or Na2s2O3 coexposure group and 1 μg/ml agNP exposure alone (P,0.05). cDenotes significant difference between each agNP (5 μg/ml) plus gsh or Na2s2O3 coexposure group and 5 μg/ml agNP exposure alone (P,0.05). dDenotes significant difference between each AgNP (15 μg/ml) plus gsh or Na2s2O3 coexposure group and 15 μg/ml agNP exposure alone (P,0.05). Abbreviations: E. coli, Escherichia coli; agNP, silver nanoparticle; cit, citrate; gsh, glutathione; MPa, mercaptopropionic acid; Mha, mercaptohexanoic acid; MPs, mercaptopropionic sulfonic acid.