Surface hydrolysis-mediated PEGylation of poly(N-isopropyl acrylamide) based nanogels

@inproceedings{Peters2017SurfaceHP,
  title={Surface hydrolysis-mediated PEGylation of poly(N-isopropyl acrylamide) based nanogels},
  author={Jonathan T. Peters and Stanley Verghese and Deepak Subramanian and Nicholas A Peppas},
  booktitle={Regenerative biomaterials},
  year={2017}
}
In this work, poly(N-isopropyl acrylamide-co-acrylamide) [P(NIPAAm-co-AAm)] nanogels were modified by hydrolysis above the lower critical solution temperature (LCST) to localize carboxylic acid functional groups at the surface (surface hydrolysis). PNIPAAm copolymerized with 15% and 20% nominal AAm in the feed were prepared and compared to equivalent… CONTINUE READING