Surface expression, polarization, and functional significance of CD73 in human intestinal epithelia.

Abstract

During active intestinal inflammation polymorphonuclear leukocytes (PMN) transmigrate into the lumen and release 5'-AMP (J. Clin. Invest. 1993. 91:2320-2325). 5'-AMP is converted to adenosine by the apical epithelial surface with subsequent activation of electrogenic Cl- secretion (the basis of secretory diarrhea) via apical A2b adenosine receptors (J. Biol… (More)

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Cite this paper

@article{Strohmeier1997SurfaceEP, title={Surface expression, polarization, and functional significance of CD73 in human intestinal epithelia.}, author={Gregg R. Strohmeier and Wayne Lencer and Thomas W. Patapoff and L. Thompson and Synn{\"o}ve Carlson and Signe Moe and Donna Carnes and Randal J Mrsny and Jonathan Madara}, journal={The Journal of clinical investigation}, year={1997}, volume={99 11}, pages={2588-601} }