Surface epithelium of the ovary following oral administration of hexachlorobenzene to the monkey.

@article{Babineau1991SurfaceEO,
  title={Surface epithelium of the ovary following oral administration of hexachlorobenzene to the monkey.},
  author={K A Babineau and Ameet Singh and John J Jarrell and Danielle Villeneuve},
  journal={Journal of submicroscopic cytology and pathology},
  year={1991},
  volume={23 3},
  pages={457-64}
}
Hexachlorobenzene (HCB) is a toxic and carcinogenic chemical that has been implicated in female reproductive dysfunctions, including destruction of ovarian follicles in primates. The purpose of this study was to determine the effects of HCB on ovary surface epithelium (SE). Gelatin capsules containing HCB mixed with glucose were given to 16 cynomolgus monkeys housed under controlled conditions in dosages of 0.0, 0.1, 1.0, or 10.0 mg/kg body weight daily, for 90 days; the first group served as… CONTINUE READING

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