Surface epithelial cell damage induced by restraint and water-immersion stress in rats effects of 16,16-dimethyl prostaglandin E2 on stress-induced gastric lesions.

Abstract

The time-course of gastric mucosal surface epithelial cell damage and macroscopically visible lesions in response to restraint and water-immersion stress (22 degrees C) in rats was examined, and the effects on it of 16,16-dimethyl prostaglandin E2 (dmPGE2) were compared with those of papaverine, timoprazole and atropine. The stress produced surface… (More)

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@article{Ohno1987SurfaceEC, title={Surface epithelial cell damage induced by restraint and water-immersion stress in rats effects of 16,16-dimethyl prostaglandin E2 on stress-induced gastric lesions.}, author={T. Ohno and Noriyuki Hirose and Hidetaka Uramoto and T. Ishihara and Seiichi Okabe}, journal={Japanese journal of pharmacology}, year={1987}, volume={45 3}, pages={405-15} }