Surface-enhanced Raman scattering of whole human blood, blood plasma, and red blood cells: cellular processes and bioanalytical sensing.

@article{Premasiri2012SurfaceenhancedRS,
  title={Surface-enhanced Raman scattering of whole human blood, blood plasma, and red blood cells: cellular processes and bioanalytical sensing.},
  author={W Ranjith Premasiri and Jeffrey C. Lee and Lawrence D. Ziegler},
  journal={The journal of physical chemistry. B},
  year={2012},
  volume={116 31},
  pages={9376-86}
}
SERS spectra of whole human blood, blood plasma, and red blood cells on Au nanoparticle SiO(2) substrates excited at 785 nm have been observed. For the sample preparation procedure employed here, the SERS spectrum of whole blood arises from the blood plasma component only. This is in contrast to the normal Raman spectrum of whole blood excited at 785 nm and open to ambient air, which is exclusively due to the scattering of oxyhemoglobin. The SERS spectrum of whole blood shows a storage time… CONTINUE READING

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