Surface-enhanced Raman Spectral Measurements of 5-Fluorouracil in Saliva

  title={Surface-enhanced Raman Spectral Measurements of 5-Fluorouracil in Saliva},
  author={Stuart Farquharson and Alan D Gift and Chetan Shende and Frank Inscore and Beth Ordway and Carl Farquharson and John R. Murren},
The ability of surface-enhanced Raman spectroscopy (SERS) to measure 5-fluorouracil (5-FU) in saliva is presented. The approach is based on the capacity of Raman spectroscopy to provide a unique spectral signature for virtually every chemical, and the ability of SERS to provide microg/mL sensitivity. A simple sampling method, that employed 1-mm glass capillaries filled with silver-doped sol-gels, was developed to isolate 5-FU from potential interfering chemical components of saliva and… CONTINUE READING
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Publications referenced by this paper.
Showing 1-10 of 55 references

Analysis of 5-fluorouracil in saliva using surface-enhanced Raman spectroscopy

S. Farquharson, C. Shende, F. E. Inscore, P. Maksymiuk, A. D. Gift
J. Raman Spectrosc • 2005
View 1 Excerpt

Analysis of the chemotherapy drug 5fluorouracil and its metabolites by surface-enhanced Raman spectroscopy

A. D. Gift, C. Shende, F. E. Inscore, S. Farquharson
Proc . SPIE • 2005
View 3 Excerpts

Chemical separation and plural point, surface-enhanced Raman spectral detection using metal-doped sol-gels

S. Farquharson, P. Maksymiuk
U.S. Pat • 2005
View 1 Excerpt

Detection of 5fluorouracil in saliva using surface-enhanced Raman spectroscopy

S. Farquharson, A. Gift, +3 authors J. Murren
Vib. Spectrosc • 2005
View 3 Excerpts

Five minute analysis of chemotherapy drugs and metabolites in saliva: Evaluating Dosage

A. D. Gift, C. Shende, F. E. Inscore, P. Maksymiuk, S. Farquharson
Proc . SPIE • 2004
View 1 Excerpt

Identification and characterization of pharmaceuticals using Raman and surface-enhanced Raman Scattering

S. Cîntă Pînzaru, I. Pavel, N. Leopold, W. Kiefer
J. Raman Spectrosc • 2004
View 1 Excerpt

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