Surface distribution and recycling of the low density lipoprotein receptor as visualized with antireceptor antibodies

@article{Anderson1982SurfaceDA,
  title={Surface distribution and recycling of the low density lipoprotein receptor as visualized with antireceptor antibodies},
  author={Richard G. W. Anderson and Michael Scott Brown and Ulrike Beisiegel and Joseph L Goldstein},
  journal={The Journal of Cell Biology},
  year={1982},
  volume={93},
  pages={523 - 531}
}
For more than 45 years biologists have known that cells internalize extracellular fluid and its contents by fluid-phase endocytosis, an inefficient process for the uptake of molecules that are present at low concentrations. More recently, animal cells have been found to express surface receptors that bind, and thereby concentrate, certain molecules so that they can be taken up in large amounts even when they are present at low concentrations outside the cell. Ligands that are internalized in… CONTINUE READING
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Recyclin g of cell surface receptors : observations from the LDL receptor system

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Evidence for the sorting of endocytic vesicle contents during the receptor - mediated transport of IgG across the newborn rat intestine

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Monensi n interrupts the recycling of low density lipoprotein receptors in human fibroblasts

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Monoclonal antibodies to the low density lipoprotein receptor as probes for study of receptor - mediated endocytosis and the genetics of familial hypercholesterolemia

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