Surface-core relationships in human low density lipoprotein as studied by infrared spectroscopy.

The secondary structure of human apolipoprotein B at 37 degrees C is estimated to be 24% alpha-helix, 23% beta-sheet, 6% beta-turns, 24% unordered structure, and 24% "beta-strands," characterized by a band around 1618 cm-1, and consistent with extended string-like chains in contact with the lipid moiety not forming beta-sheets. When cooled to a temperature… CONTINUE READING