Surface components of airborne particulate matter induce macrophage apoptosis through scavenger receptors.

@article{Obot2002SurfaceCO,
  title={Surface components of airborne particulate matter induce macrophage apoptosis through scavenger receptors.},
  author={Chrysanthus J Obot and Maria T. Morandi and Thomas P. Beebe and Raymond F. Hamilton and Andrij Holian},
  journal={Toxicology and applied pharmacology},
  year={2002},
  volume={184 2},
  pages={
          98-106
        }
}
Epidemiology studies have linked mortality, increased asthma morbidity, and other respiratory disorders in urban areas to increases in fine airborne particulate matter (PM) concentrations. However, neither the bioactive components of PM nor the biological mechanisms of the reported health effects have been elucidated. A number of studies have implicated soluble metals, the strong acid fraction, and/or other components of PM as possible bioactive mediators. Alveolar macrophage (AM) apoptosis… CONTINUE READING
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