Surface-based morphometry reveals distinct cortical thickness and surface area profiles in Williams syndrome.

@article{Green2016SurfacebasedMR,
  title={Surface-based morphometry reveals distinct cortical thickness and surface area profiles in Williams syndrome.},
  author={Tamar Green and Kyle C Fierro and Mira M. Raman and Manish Saggar and Kristen E Sheau and Allan L. Reiss},
  journal={American journal of medical genetics. Part B, Neuropsychiatric genetics : the official publication of the International Society of Psychiatric Genetics},
  year={2016},
  volume={171B 3},
  pages={
          402-13
        }
}
Morphometric investigations of brain volumes in Williams syndrome (WS) consistently show significant reductions in gray matter volume compared to controls. Cortical thickness (CT) and surface area (SA) are two constituent parts of cortical gray matter volume that are considered genetically distinguishable features of brain morphology. Yet, little is known about the independent contribution of cortical CT and SA to these volumetric differences in WS. Thus, our objectives were: (i) to evaluate… CONTINUE READING
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