Surface-assisted laser desorption/ionization mass spectrometry

@article{Dattelbaum2006SurfaceassistedLD,
  title={Surface-assisted laser desorption/ionization mass spectrometry},
  author={Andrew Martin Dattelbaum and Srinivas Iyer},
  journal={Expert Review of Proteomics},
  year={2006},
  volume={3},
  pages={153 - 161}
}
Laser desorption/ionization mass spectrometry (MS) is rapidly growing in popularity as an analytical characterization method in several fields. The technique shot to prominence using matrix-assisted desorption/ionization for large biomolecules (>700 Da), such as proteins, peptides and nucleic acids. However, because the matrix, which consists of small organic molecules, is also ionized, the technique is of limited use in the low-molecular-mass range (<700 Da). Recent advances in surface science… 

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...

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