Surface and internal galactosyl receptors are heterooligomers and retain this structure after ligand internalization or receptor modulation.

@article{Herzig1990SurfaceAI,
  title={Surface and internal galactosyl receptors are heterooligomers and retain this structure after ligand internalization or receptor modulation.},
  author={M. Herzig and P. Weigel},
  journal={Biochemistry},
  year={1990},
  volume={29 27},
  pages={
          6437-47
        }
}
  • M. Herzig, P. Weigel
  • Published 1990
  • Chemistry, Medicine
  • Biochemistry
  • We have developed a specific chemical affinity reagent for the hepatic galactosyl receptor (GalR) by derivatizing asialoorosomucoid (ASOR) with the homobifunctional N-hydroxysuccinimide (NHS) ester cross-linker disuccinimidyl suberate [Herzig, M. C. S., & Weigel, P. H. (1989) Biochemistry 28, 600]. NHS-ASOR cross-links with 30-50% efficiency to the three GalR subunits, designated rat hepatic lectins (RHL) 1, 2, and 3. Here, we examined the subunit structure of both surface and internal… CONTINUE READING
    17 Citations
    Functional galactosyl receptors on isolated rat hepatocytes are hetero-oligomers.
    • 10
    Endocytosis and function of the hepatic asialoglycoprotein receptor.
    • P. Weigel
    • Biology, Medicine
    • Sub-cellular biochemistry
    • 1993
    • 36
    Fatty Acylation of the Rat Asialoglycoprotein Receptor
    • 21
    • PDF