• DOI:10.1021/BI00479A015
Corpus ID: 24491775

Surface and internal galactosyl receptors are heterooligomers and retain this structure after ligand internalization or receptor modulation.

@article{Herzig1990SurfaceAI,
  title={Surface and internal galactosyl receptors are heterooligomers and retain this structure after ligand internalization or receptor modulation.},
  author={M. Herzig and P. Weigel},
  journal={Biochemistry},
  year={1990},
  volume={29 27},
  pages={
          6437-47
        }
}

M. Herzig, P. Weigel

Published 1990

Chemistry, Medicine

Biochemistry

We have developed a specific chemical affinity reagent for the hepatic galactosyl receptor (GalR) by derivatizing asialoorosomucoid (ASOR) with the homobifunctional N-hydroxysuccinimide (NHS) ester cross-linker disuccinimidyl suberate [Herzig, M. C. S., & Weigel, P. H. (1989) Biochemistry 28, 600]. NHS-ASOR cross-links with 30-50% efficiency to the three GalR subunits, designated rat hepatic lectins (RHL) 1, 2, and 3. Here, we examined the subunit structure of both surface and internal… CONTINUE READING

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