Surface-adhering Human Leucocytes: An In Vitro Model for Cytotoxicity Testing of Fluids.

Abstract

A rapid screening method was developed for assessment of the toxic effects of fluid materials on the respiratory burst response of polymorphonuclear neutrophils (PMNLs). The method was used to detect adverse effects of peritoneal dialysis (PD) fluids. Intoxication of the respiratory burst response attenuates the bacterial killing capacity of PMNLs, and… (More)

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