Surface Vulnerability of Cerebral Cortex to Major Depressive Disorder

  title={Surface Vulnerability of Cerebral Cortex to Major Depressive Disorder},
  author={Daihui Peng and Feng Shi and Gang Li and Drew Fralick and Ting E Shen and Meihui Qiu and Jun Liu and Kaida Jiang and Dinggang Shen and Yi-ru Fang},
  booktitle={PloS one},
Major depressive disorder (MDD) is accompanied by atypical brain structure. This study first presents the alterations in the cortical surface of patients with MDD using multidimensional structural patterns that reflect different neurodevelopment. Sixteen first-episode, untreated patients with MDD and 16 matched healthy controls underwent a magnetic resonance imaging (MRI) scan. The cortical maps of thickness, surface area, and gyrification were examined using the surface-based morphometry (SBM… CONTINUE READING
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