Surface Modification of PMMA to Improve Adhesion to Corneal Substitutes in a Synthetic Core-Skirt Keratoprosthesis.

@article{Riau2015SurfaceMO,
  title={Surface Modification of PMMA to Improve Adhesion to Corneal Substitutes in a Synthetic Core-Skirt Keratoprosthesis.},
  author={Andri K Riau and Debasish Mondal and Gary Hin-Fai Yam and Melina Setiawan and Bo Liedberg and Subbu S Venkatraman and Jodhbir S. Mehta},
  journal={ACS applied materials & interfaces},
  year={2015},
  volume={7 39},
  pages={21690-702}
}
Patients with advanced corneal disease do poorly with conventional corneal transplantation and require a keratoprosthesis (KPro) for visual rehabilitation. The most widely used KPro is constructed using poly(methyl methacrylate) (PMMA) in the central optical core and a donor cornea as skirt material. In many cases, poor adherence between the PMMA and the soft corneal tissue is responsible for device "extrusion" and bacterial infiltration. The interfacial adhesion between the tissue and the PMMA… CONTINUE READING
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